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Product Information:

PROTAC K-Ras Degrader-1

PROTAC K-Ras Degrader-1 (Compound 518) is potent K-Ras degrader based PROTAC, exhibits ≥70% degradation efficacy in SW1573 cells.

Cat. No.: EX-A3964    Purity: >98%
Chemical
Chemical structure of PROTAC K-Ras Degrader-1


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
5mg800In-stock
10mg1285In-stock
25mg2000In-stock
50mg3200In-stock
250mgInquireIn-stock


CAS No.2378258-52-5
Purity>98%
FormulaC53H62N10O10
Mol Weight999.1204
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. CREW, Andrew P., et al. MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE. WO2019195609A2.
CoACoA of PROTAC K-Ras Degrader-1
Smiles:CN1[C@@H](C[C@@H](OCCOCCOCCOCCNC2=C3C(C(N(C4C(NC(CC4)=O)=O)C3=O)=O)=CC=C2)C1)COC5=NC(N6C[C@@H](N(C(C=C)=O)CC6)CC#N)=C7C(CN(C8=CC=CC9=C8C=CC=C9)CC7)=N5

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